El Angiofibroma nasofaríngeo juvenil es un tumor benigno vascular (pero que tardíamente Se localiza en la pared posterolateral de la grita nasal a nivel del vínculo de la apófisis esfenoidal del hueso palatino. Esta localización conforma el. Nasal cavity, paranasal sinuses, nasopharynx – Nasopharyngeal angiofibroma. Juvenile nasopharyngeal angiofibroma (JNA) is a rare and benign but locally in the nasopharynx and nasal cavity, leading to manifestations such as nasal.

Author: JoJoramar Sabar
Country: Zimbabwe
Language: English (Spanish)
Genre: Automotive
Published (Last): 17 March 2010
Pages: 315
PDF File Size: 17.52 Mb
ePub File Size: 18.55 Mb
ISBN: 676-4-85534-851-9
Downloads: 56913
Price: Free* [*Free Regsitration Required]
Uploader: Fegami

Genetic evidence for an androgen-dependent tumor? The combination of different accesses to the tumor can be required 9.

Nasopharyngeal angiofibroma is a histologically and biologically benign tumor with aggressive behavior due to its location and associated symptoms including significant epistaxis and nasal angjofibroma Endoscopic Laser-assisted excision of aniofibroma nasopharyngeal angiofibromas. It impinges on adjacent structures and causes pressure erosion of bone.

Endoscopic surgery is less invasive than open surgery, causing less damage to the patient.

Fisch classification, however, is currently accepted. To assess the prevalence of complications in endoscopic or endoscopic-assisted surgical treatment of JNA with minimal intracranial invasion. Based on the clinical and radiological features, JNA is classified into three types.

The blood vessels are slit-like or dilated, organized in clusters and are of different calibers. Analysis of these 13 patients suggests that fully endoscopic surgery is viable even in advanced cases of JNA. The demographic profile, surgical techniques used, immediate and delayed complications, and recurrence rate of the sample are listed in Table 1.

Diagnosis of JNA is made by complete history, clinical examination, radiography, nasal endoscopy; and specialized imaging techniques such as arteriography, CT, and magnetic resonance imaging MRI.

Clinical examination reveals a firm and friable mass in anviofibroma nasopharynx and nose. Summary and related texts. Articles from Journal of Oral and Maxillofacial Pathology: This was a retrospective cohort study of all patients with JNA with intracranial extension Radkowski grade IIIa treated with endoscopic, endoscopic-assisted, and external surgery from January of to May of When diagnosed early the patients are treated with a combination of preoperative embolization and surgical resection providing a good prognosis.


Pancoast tumor Solitary pulmonary nodule Central lung Peripheral lung Juvdnil leiomyoma. Cases and figures Imaging differential diagnosis. To retrospectively describe our experience in the diagnosis and treatment of patients with juvenile nasopharyngeal angiofibroma.

Current debate involves angifoibroma hamartoma and vascular malformation theories. The classic triad of epistaxis, unilateral nasal obstruction, and a mass in the nasopharynx suggests a diagnosis of nasopharyngeal angiofibroma and is supplemented by imaging 11,12,13,14, Moreover, the mean blood loss in these patients was mL.

Histopathologically Nasl shows a fibrocellular stroma with spindle cells and haphazardly arranged collagen interspersed with an irregular vascular pattern.

Intracranial extension can however occur. From a triangular region formed by the foramen ovale, a round and lacerated tumor may reach the middle fossa, migrating to the parasellar region and remaining generally extradual and lateral to the cavernous sinus.

Ear Nose Throat J. A year-old male patient presented with a painless, progressive swelling in the upper jaw since 2 weeks. Nasal cavity Esthesioneuroblastoma Nasopharynx Nasopharyngeal carcinoma Nasopharyngeal angiofibroma Larynx Laryngeal cancer Laryngeal papillomatosis. On examination, it may be seen as a pale reddish-blue mass.

Juvenile nasopharyngeal angiofibroma

JNA is benign but locally destructive. Connective tissue was fibro-cellular with irregular pattern and plump fibroblasts [ Figure 6 ]. Definitive Radiotherapy for Aangiofibroma Nasopharyngeal Angiofibroma. Professionals Review article English Clinical practice guidelines English The hormonal influence in JNA remains controversial.

Intraoral swelling was diffuse, obliterating the vestibule and extending from the lateral incisor anteriorly till the pharynx posteriorly [ Figure 1 ].

Pathology Outlines – Nasopharyngeal angiofibroma

Markers of vascular differentiation, proliferation and tissue remodeling in juvenile nasopharyngeal angiofibromas. Sanchez de Guzman G. One developed oculomotor nerve palsy with CT findings indicative of cavernous sinus thrombosis, and the other sustained optic and oculomotor nerve injury manifesting as decreased visual activity and ptosis.


Prognosis for nasopharyngeal angiofibroma is favorable. Invasion of the intracranial region may lead to cranial nerve palsy.

As previously angiofibromw, this case series was restricted to non-neurosurgical routes; patients who required craniotomy due to tumor extension Radkowski grade IIIb were angiofibtoma. It is, as the name suggests, very vascular and a biopsy can sometimes be fatal. Introduction Although it is a rare neoplasm, accounting for less than 0. The tumor invades the infratemporal fossa or orbit without intracranial involvement.

A new endoscopic staging system for angiofibromas. Relative distribution of the tumours of ear, nose and throat in the paediatric patients.

Juvenile nasopharyngeal angiofibroma

We analyzed findings in 20 patients who underwent surgery between and Tumors may invade the anterior fossa through the ethmoid and sphenoid sinuses, being nazal frequent in the middle fossa and remaining extradural 8,9, Retrieved from ” https: The tumor is limited to the sphenopalatine foramen, nasopharynx, and nasal cavity without bone destruction.

Longer duration of surgery is associated with greater changes in body homeostasis due to surgical trauma. How to cite this article.

The endoscope has proved itself to be an important tool for visualizing the entire extent of these tumors, particularly in the region of the superior orbital angiofibdoma, cavernous sinus, and even in the pterygopalatine fossa, where the presence of residual lesions is not unusual after resection of tumors as extensive as those described in the present study.