Learn more about Choline uses, effectiveness, possible side effects, CHOLINE. OTHER NAME(S). Bitartre de Choline, Chlorure de Choline, Choline. Structure, properties, spectra, suppliers and links for: choline chloride, chlorure de choline [French] [INN]. choline chloride [INN]. More CHOLINE. Choline chloride ≥99%; CAS Number: ; EC Number: ; Synonym: (2-Hydroxyethyl)trimethylammonium chloride; Linear Formula: C5H14ClNO;.

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In animal models, long-term withdrawal of choline from the diet can cause hepatocarcinoma Subscribe now so you can enter the Natural Medicines Comprehensive Database. Many people think choline, phosphatidylcholine, and lecithin are synonymous. Preliminary clinical research shows that giving liquid choline chloride Vitamin Research Products orally at doses to achieve adequate intake AI daily for weeks does not increase plasma choline levels in infants with choline deficiency due to intestinal failure.

Effort is made to ensure that the information contained in this Natural Medicines monograph is accurate at the time it was published. For example, choline can be oxidized to betaine which serves as a methyl donor to convert homocysteine to methionine, then S-adenosylmethionine Therefore, it is possible that higher maternal intake of choline is needed to observe a benefit. Fetal alcohol spectrum disorders FASD.

Irritates lungs, eyes, skin Alfa Aesar A Views Read Edit View history. Taking choline orally does not improve memory in elderly people with memory loss A cross-sectional analysis of results from observational and clinical research shows that low dietary chlourre of choline is associated with increased fibrosis in postmenopausal women with nonalcoholic fatty liver disease but not in children, men, or premenopausal women with this condition.

Chlorure de choline

In the laboratory, choline can be prepared by methylation of dimethylethanolamine choorure methyl chloride. Choline is a component of phosphatidylcholine, which is a component of lecithin. Choline has traditionally been considered a B vitamin.


An average diet supplies mg of choline daily Choline is produced in the liver via the methylation of phosphatidylethanolamine.

Deficiency of choline is uncommon except in people receiving long-term total parenteral nutrition TPN Some anecdotal evidence suggests that taking choline 1 grams orally four or five times daily improves motor function in patients with cerebellar ataxia Retrieved 19 September Comment on this record.

There is concern that choline might increase the risk of colorectal cancer.

choline chloride (CHEBI)

For children years the AI is mg per fholine years, mg per day; years, mg per day ; for infants less than 6 months, mg per day; infants months, mg per day For details about our evidence-based approach, see our Editorial Principles and Process. Retrieved from ” https: However, we cannot guarantee the information is error-free and disclaim any liability or responsibility for any reliance on it.

In one population study, consuming large amounts of choline was associated with an increased risk of xholine cancer in women, even after adjusting for red meat intake Taking choline orally does not seem to be effective for delaying fatigue in endurance sports If you have comments or suggestions on something that should be reviewed or included, chloruure tell the editors.

Quaternary ammonium compounds Alcohols. It is a white, water soluble salt used mainly in animal feed. Except for any possible exceptions written into your License Agreement, no reproduction of this monograph or any content from Natural Medicines is permitted without written permission from the publisher.

High dholine can increase the risk of adverse effects Daily Upper Intake Levels UL, the highest level of intake that is likely to pose no risk of adverse effects for choline are 1 gram daily for children years, 2 grams for children years, 3 cholins for children years, and 3.


Choline also seems to play a role in the development of neural tube defects Publication or Magazine Article. Also, taking ch,orure prior to participating in exhaustive, load-carrying exercise does not improve dexterity, upper or lower body strength, grip strength, or run time-to-exhaustion following exercise compared to placebo Choline chloride is mass-produced with world production estimated at tons in However, when only children aged 2.

Compounds with the same molecular formula Compounds with the same skeleton Use this molecule in a structure search.

For asthma, mg three times daily has been used Research on the effect of maternal choline intake on cognitive development is conflicting. Adequate Intake AIas established by the Food and Nutrition Board of the National Institute of Medicine, for adults is choine per day for males and lactating women; females, mg per day; pregnant females, mg per day Other names hepacholine, biocolina and lipotril.

Choline chloride

Taking choline orally does not reduce symptoms of schizophrenia Choline is used in cell membrane phospholipids and as a methyl donor for the synthesis of many endogenous compounds. Web-based Article blog or commentary. Choline is safe in adults when taken in doses below the tolerable upper intake level UL of 3. This cylorure was last edited on 1 Septemberat The National Academy of Medicine formerly the Institute of Medicine states that doses up to 3 grams daily for pregnant cglorure lactating women up to 18 years of age, and 3.

It is fully referenced and updated daily.