The effects of the aqueous crude extract (5%) of Eugenia punicifolia on cholinergic nicotinic neurotransmission were investigated. Actions of. Eugenia punicifolia (Kunth) DC (Myrtaceae), popularly known as pedra-ume-caá, pedra-ume, murta, or muta, is a shrub found mainly in the. Figure 16 Body weight evolution in rats with acetic acid-induced gastric ulcers treated with oral administration of vehicle, lansoprazole.

Author: Vom Ditaur
Country: Germany
Language: English (Spanish)
Genre: Life
Published (Last): 22 October 2018
Pages: 343
PDF File Size: 16.71 Mb
ePub File Size: 10.54 Mb
ISBN: 979-3-82130-994-2
Downloads: 33373
Price: Free* [*Free Regsitration Required]
Uploader: Arashinos

Li et al[ 49 ] reported enhanced expression of MMP-9 in the margin of the ulcer and suggested that this finding may be indicative of inflammation and poor wound healing. Beach Cherry Eugenia punicifolia Though punicifoliq common in its native range, the Beach Cherry is little know elsewhere in the world. Research methods We used a rat model of acetic acid-induced gastric ulcers to evaluate the healing effect of HEEP.

There was a problem providing the content you requested

The animals were kept in cages with raised, wide-mesh floors to prevent coprophagy. Gurusamy KS, Pallari E. Berg Eugenia suffruticosa var. Am J Dig Dis.

Beach Cherry – Eugenia punicifolia

A comparison of methods for determining total body protein. The data represent relative expression of caspase-8 normalized to the expression of housekeeping genes actin. The data represent relative expression of Bcl-2 normalized to the expression of housekeeping genes actin. July 4, Revised: We evaluated the sex-specific effects of HEEP in the healing of gastric ulcers induced by acetic acid in rats. No statistically significant differences were found. Scand J Gastroenterol Suppl.

Medical versus surgical treatment for refractory or recurrent peptic ulcer. June 13, Peer-review started: These findings are useful for developing novel and safe eugfnia for gastric ulcers. Evaluation of the wound healing potential of Wedelia trilobata L.


World Checklist of Myrtaceae: A vehicle, lansoprazole, or HEEP was administered for 14 d after ulcer induction. MMPs are divided into several groups based on their substrate specificity and cellular localization; such groups include collagenases, gelatinases, stromelysins, membrane-type MMPs, and others[ 50 ].

Syzygium malaccense Malay Apple.

eugeniq Furthermore, there was no significant difference in lesion area between males and OVZ females who received the same treatment Figure 1suggesting that the absence of female sex hormones diminishes healing. Role of epidermal growth factor in healing of chronic gastroduodenal ulcers in rats.

The following chemicals and reagents were used: D Grade E Poor: Eugenia patrisii Turtle Berry. Myrcianthes fragrans Simpson’s Stopper. The injection of acetic acid into the gastric mucosa induces the development of deep gastric ulceration and gastric mucosal damage directly associated with extracellular matrix degradation, in which zinc-dependent MMPs play a crucial role. Syzygium jambos Rose Apple.

Another step taking place in this process is the mucosal reconstruction by formation of granulation tissue at the base of the ulcer, formation of new vessels, and restoration of the glandular architecture[ 45 ].

Data were collected at the end of treatment. One of the least understood aspects of gastric ulcers is the chronicity of the disease, which is characterized by repeated episodes of healing and re-exacerbation, posing a challenge to physicians and a burden for patients[ 31 ].

Sex-specific effects of Eugenia punicifolia extract on gastric ulcer healing in rats

At the ulcer margin, epithelial cells proliferate and migrate to the granulation tissue to cover re-epithelialize the ulcer and initiate reconstruction of the glands within the ulcer scar[ 5556 ].

The integrity of the gastric mucosa is highly dependent on the continuous generation of prostaglandins by COX-1 and COX-2[ 46 ].


Eugenia punicifolia is a medicinal plant used to treat inflammation and wounds. The oestrous cycle in the rat and its associated phenomena.

Finally, HEEP treatment is safe and unlikely to exhibit subacute toxicity or cytotoxicity. The organs were removed and weighed. Use for planting in pots 50 cm high and 40 cm wide red soil and the same mixture as aboveit must be ensured that a 4 cm drainage layer is placed on the bottom of the pot to ensure a rapid withdrawal. Finally, the gels were stained with Coomassie Brilliant Blue R The 84 animals included in the study 30 males, 30 intact females, 24 ovariectomized females were divided into nine groups with individuals each.

Eugenia punicifolia (Kunth) DC.

Among females, HEEP was associated with a very significant reduction in lesion area, both in cycling rats The protective role of female sex hormones likely accounts for the higher incidence of gastric ulcers in men vs women[ 34 ]. Estradiol treatment ameliorates acetic acid-induced gastric and colonic injuries in rats. Wound healing acceleration of a novel transforming growth factor-beta inducer, SEK The punicioflia test measures the expansion of a cell population on surfaces.

An integrative study of the biological effects of Serjania marginata Casar. For this test, the protein extracts punicfolia obtained as described above for zymography. Melaleuca incana Gray Honey Myrtle. Berg Eugenia romana var.

However, this therapy is associated with several side effects and poor quality of ulcer healing.