Herba Centellae consists of the dried aerial parts or the entire plant of Centella ghortapre, gotu kola, gotukola, herba pegagan, herba kakikuda, hydrocotyle. Download Citation on ResearchGate | On Mar 25, , Islamiyah Neda Rahayu and others published UJI EFEK HEPATOPROTEKTIF INFUS HERBA. Mubarokah A. Uji efek sedatif ekstrak metanol herba pegagan (centella asiatica) terhadap mencit putih jantan dengan metode potensiasi.

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A slender trailing herb, rooting at the nodes. Pharmacology Experimental pharmacology The pharmacological activity of Centella asiatica is thought to be due to several pevagan constituents, including asiaticoside, asiatic acid, and madecassic acid Extract of Herba Centellae effectively treated stress-induced stomach and duodenal ulcers in humans 10 Review of Brasilian medicine, Clinical trials of the drug have demonstrated its antiulcer activity after oral administration 2839 Package in well-closed, light-resistant containers.

Allergic contact dermatitis due to Centella asiatica extract. Asiaticoside extracted from Centella asiaticaits therapeutic uses in healing of experimental or refractory wounds, leprosy, skin tuberculosis, and lupus.

Evaluation of the healing activity of Hydrocotyle tincture in the treatment of wounds. In an open clinical study, treatment of 20 patients with soiled wounds and chronic or recurrent atony with a galenical formulation containing Stuttgart, Deutscher Apotheker Verlag, The pharmacological activity of Centella asiatica is thought to be due to several saponin constituents, including asiaticoside, asiatic acid, and madecassic acid Medicinal plants in Viet Nam.


Adverse reactions Allergic contact dermatitis has been associated with topical application of C. Radioactive residues For analysis of strontium, iodine, caesium, caesium, and plutonium, see WHO guidelines on quality control methods for medicinal plants Pegaban C, Bourde J.

Reticuloses and epidermal tumors in hairless mice after topical skin applications of cantharidin and asiaticoside. Apropos of 50 cases. Derivatives of Centella asiatica used against leprosy. The mechanism of action appears to be associated with pegwgan central nervous system-depressant activity of C.

Pegagan gajah

Warnings No information available. Preparations for internal use: African pharmacopoeia1st ed. Organoleptic properties Colour, greyish green; odour, characteristic; taste, slightly bittersweet 45.

Action of the titrated extract of Centella asiatica in the cicatrization of leg ulcers 10 mg tablets. Herba Centellae is reported to be used in the treatment of leprous ulcers and venous disorders 56810 After 3 weeks of treatment, 17 of the patients were completely healed and the ulcer size in the remaining 5 patients was decreased Local application of an extract of the drug to second- and third-degree burns expedited healing, prevented the shrinking and swelling caused by infection, pegagqn further inhibited hypertrophic scar formation I dans une population lepreuse presentant des maux perforants plantaires.


WHO Monographs on Selected Medicinal Plants – Volume 1: Herba Centellae

Macroscopic and microscopic examinations; and microchemical tests for the presence of triterpenes and reducing sugars 14. Nature, Clinical study of a new antikeloid agent. Uses described in folk medicine, not supported by experimental or clinical data Therapy of albinism, anaemia, asthma, bronchitis, cellulite, cholera, measles, constipation, dermatitis, diarrhoea, dizziness, dysentery, dysmenorrhoea, dysuria, epistaxis, epilepsy, haematemesis, haemorrhoids, hepatitis, hypertension, jaundice, leukorrhoea, nephritis, nervous disorders, neuralgia, rheumatism, smallpox, syphilis, toothache, urethritis, and varices; and as an antipyretic, analgesic, anti-inflammatory, and “brain tonic” agent 457.

The major principles in Herba Centellae are the triterpenes asiatic acid and madecassic acid, and their derived triterpene ester glycosides, asiaticoside and madecassoside 810 The mechanism of action appears to be twofold: Semaine hospitaux de Paris, Chakrabarty T, Deshmukh S.

To be established in accordance with psgagan requirements.

Pharmacognosy9th ed. Mayall RC et al.