Konjungtivitis Vernal – Download as Powerpoint Presentation .ppt), PDF File . pdf), Text File .txt) or view presentation slides online. Vernal keratoconjunctivitis (VKC), atopic keratoconjunctivitis (AKC), and giant papillary conjunctivitis (GPC) constitute the remaining subtypes. Management of Vernal Keratoconjunctivitis. Multiple pharmacologic agents may be used to provide varying degrees of relief. Mucolytic agents.

Author: Goltigore Faushakar
Country: Peru
Language: English (Spanish)
Genre: Life
Published (Last): 28 September 2009
Pages: 493
PDF File Size: 18.17 Mb
ePub File Size: 14.72 Mb
ISBN: 605-5-87444-959-7
Downloads: 77763
Price: Free* [*Free Regsitration Required]
Uploader: Zolojora

Additionally, adult patients with VKC may respond more vernxl to konjjungtivitis cyclosporin therapy [16]. Vernal keratopathy includes 5 types of lesions.

Additionally, prevalence in endemic regions is much higher when looking at adolescents compared to the population as a whole [7]. D ICD – Topical mast cell stabilizers cromolyn sodium, nedocromil sodium, and lodoxamide are typically used with topical antihistamines and have been shown to be effective in moderate presentations of VKC [13]. Eur Rev Med Pharmacol Sci, It is difficult to obtain an accurate prevalence as many patients may not present to clinics as they may have a mild form of the disease and the condition is largely self-limiting.

Males are affected more than females, but this difference becomes smaller as age increases [3]. Badr, Corneal ectasia in vernal keratoconjunctivitis. This page has been accessedtimes.

Vernal keratoconjunctivitis VKC konjyngtivitis an atopic condition of the external ocular surface. VKC was originally thought to be due to a solely IgE mediate reaction via mast cell release [1].

Create account Log in. The Academy uses cookies to analyze performance and provide relevant personalized content to users of our website. If seasonal recurrence is known, it is suggested that mast-cell stabilization therapy be initiated prior to the season in which symptoms are encountered and continued throughout the season [6].

VKC is seen more often in patients who have atopic family histories, but no clear correlation with specific genetic loci has been elucidated [2]. The majority of VKC occurs in patients between the ages of years old with vdrnal age of onset between years old; however there are reports of patients as young as 5-months-old [2, 11]. Based on severity, authors have classified VKC into clinical grades: Mannis, and Edward J.


InGabrielides identified eosinophils in conjunctival secretions as well of the peripheral blood of VKC patients. In other projects Wikimedia Commons. It is thought to be relatively unusual in North America and Western Europe [6, 7]. J Clin Diagn Res. VKC is a condition seen primarily in hot and dry climates most commonly in West Africa and the Mediterranean basin [1, 2].

Thought has been given to a possible endocrine method as well as there is a decrease in symptoms and prevalence after puberty [1, 2]. Depending on region and climate, prevalence of VKC can vary widely. Enroll in the Residents and Fellows contest.

It characteristically affects young males in hot dry climates in a seasonal manner; however this is not always the rule. Diseases of the eye and adnexa Disorders of conjunctiva Rare diseases.

Vernal keratoconjunctivitis – Wikipedia

Removal of any and all possible allergens as well as conservative management such as cool compresses and lid scrubs make up the first line veranl therapy [13].

In some patients symptoms may persist beyond childhood, which in some cases may represent a conversion to an adult form of atopic keratoconjunctivitis [1].

InTrantas characterized the spectrum of corneal changes seen in VKC [1]. Indian J Ophthalmol, A personal or family history of atopy is seen in a large proportion of VKC patients [12]. AKC verna has an older age of onset in the 2nd to 5th decade, as opposed to onset prior to age 10 with VKC. Injection of local corticosteroid into the upper tarsal papillae can sometimes offer short term relief as well [2, 7].


Mast-cell stabilizers have a loading period to reach their full therapeutic effect [6].

VKC is thought to be an allergic disorder in which IgE mediated mechanism play a role. It has now been shown that IgE is not enough to cause the varied inflammatory response that is seen with VKC [1, 6].

Vernal keratoconjunctivitis

This page was last modified on November 28,at For instance, one European study demonstrated the prevalence was between 1. Retrieved from ” http: Am J Ophthalmol, Barot, RK et al. Additionally, AKC is typically more chronic in nature and more commonly results in scarring of the cornea and conjunctival cicatrization, whereas VKC is typically more self-limiting [4, 6].

A topical antihistamine only may work in mild cases [13].

Vernal Keratoconjunctivitis

Long term immunomodulation with steroid veral agents such as cyclosporine and tacrolimus is konjungtigitis needed. Retrieved from ” https: Delhi Journal of Ophthalmology. Such patients often give family history of other atopic diseases such as hay feverasthma or eczemaand their peripheral blood shows eosinophilia and increased serum IgE levels. The increased incidence in hot regions is speculated to be secondary to a higher level of pollution by pollens and various other allergens.

Vernal keratoconjunctivitis VKC or spring catarrh is a recurrent, bilateral, and self-limiting inflammation of conjunctivahaving a periodic seasonal incidence.

A hereditary association has been suggested, but no direct genetic associations have been made.

Nonetheless, the sometimes debilitating nature of this disease when it is active necessitates therapy to control symptoms. High pulse dose with quick tapering and use of low-absorptions corticosteroids fluoromethelone, loteprednol, remexolone, etc.

December Learn how and when to remove this template message.